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Preclot AS 10pcs
Aspirin+Clopidogrel is used to prevent prevention of heart attack and stroke. It decreases the chances of having another heart attack or stroke from a disease related to your heart or blood vessels.
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✅ Description:
Preclot AS Tablet is composed of Aspirin and Clopidogrel, which act as blood thinners (anti-platelet) and prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).
Preclot AS Tablet helps in the free flow of blood, thereby preventing heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of the lungs).
Safety Advices
Alcohol
UNSAFE
Avoid consuming alcohol since it may worsen the side effects like dizziness and increased blood pressure.
Pregnancy
CONSULT YOUR DOCTOR
Preclot AS Tablet is not recommended for use during pregnancy since it may affect the fetus. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Preclot AS Tablet.
Breastfeeding
CONSULT YOUR DOCTOR
There is limited data on how Preclot AS Tablet affects breastfeeding. Please consult your doctor before starting Preclot AS Tablet.
Driving
CAUTION
Do not drive or operate machinery if you experience dizziness or drowsiness while using Preclot AS Tablet. Preclot AS Tablet can also sometimes cause blurry vision, hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.
Kidney
SAFE IF PRESCRIBED
Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Preclot AS Tablet.
Liver
SAFE IF PRESCRIBED
Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Preclot AS Tablet.
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✔️ Composition of Preclot AS Tablet
Clopidogrel + Aspirin
✔️ Uses of Preclot AS Tablet
Prevention of heart attack and stroke.
✔️ How does Preclot AS Tablet work?
- Clopidogrel is a prodrug that inhibits platelet activation and aggregation by irreversibly binding its active metabolite to the P2Y12 class of ADP receptors on platelets. This inhibition can be observed as early as 2 hours after a single dose, with steady-state inhibition achieved between days 3 and 7.
- Aspirin works by irreversibly inhibiting platelet cyclooxygenase, thus reducing thromboxane A2 production, which is essential for platelet aggregation and vasoconstriction.
✔️ Side Effects of Preclot AS Tablet
- Diarrhea
- Stomach pain
- Indigestion or heartburn
- Nausea or vomiting
- Muscle pain
✔️ Quick Suggestions:
- You have been prescribed Preclot AS Tablet to lower your risk of heart attack and stroke.
- Take it with food to avoid an upset stomach.
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
- Let your doctor know you are taking Aspirin + Clopidogrel before undergoing any surgical procedure.
✔️ Indication of Preclot AS Tablet
- Acute Coronary Syndrome (ACS): Used to reduce the rate of myocardial infarction (MI) and stroke in patients with non-ST-segment elevation ACS (unstable angina/non-ST-elevation MI) and acute ST-segment elevation ACS (ST-elevation MI).
- Recent MI, Recent Stroke, or Established Peripheral Arterial Disease: Indicated to reduce the rate of MI and stroke in patients with a history of recent MI, stroke, or established peripheral arterial disease.
✔️ Pharmacokinetics:
- Absorption: Clopidogrel is rapidly absorbed with at least 50% bioavailability, and peak plasma levels occur about 1 hour after dosing.
- Distribution: Clopidogrel and its main metabolite bind extensively to plasma proteins.
- Metabolism: Clopidogrel is metabolized primarily by the liver into an inactive carboxylic acid derivative.
- Excretion: Approximately 50% is excreted in urine and 46% in feces within 5 days of dosing. The elimination half-life of the main metabolite is around 8 hours.
✔️ Dosage & Administration of Preclot AS Tablet
- Standard Dose: 75 mg once daily with or without food.
- ACS Patients: Start with a 300 mg loading dose, then continue with 75 mg once daily. Aspirin (75-325 mg daily) should be used in combination with Clopidogrel.
Not recommended for children under 12 years unless the benefits outweigh the risks.
✔️ Interaction
- Aspirin: Enhances the effect of Clopidogrel on platelet aggregation.
- Heparin: No dose adjustment is needed when used together.
- NSAIDs: May increase gastrointestinal blood loss when co-administered.
- Warfarin: Caution is advised due to potential increased bleeding risk.
✔️ Contraindications
- Hypersensitivity to Clopidogrel or any component of the product.
- Active pathological bleeding (e.g., peptic ulcer, intracranial hemorrhage).
✔️ Pregnancy & Lactation
Not recommended during the third trimester. Aspirin is excreted in breast milk, so breastfeeding should be discontinued if this drug is used.
✔️ Precautions & Warnings
- May prolong bleeding time.
- Risk of Reye's syndrome if given to children with viral infections.
- Hypersensitivity reactions may occur.
- Overdose may lead to bleeding complications. Treatment may involve platelet transfusion, gastric lavage, or symptomatic treatment as necessary.
✔️ Storage Conditions:
Store below 30°C, protected from light and moisture. Keep out of the reach of children.
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and discuss all your queries related to any disease or medicine. We
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